17 Skin Repair & Quality
Treatment Series

Rejuran Skin Renewal

A consultation-led injectable treatment containing polynucleotides for selected concerns involving skin texture, hydration, fine lines, elasticity and overall skin condition.

Rejuran is a skin-quality treatment rather than a replacement for structural filler, muscle-relaxing injections or treatment for significant skin laxity. Suitability and coverage are confirmed after an in-person skin assessment.

Polynucleotide Skin Treatment
Rejuran skin treatment at LOUAVE Dermatology Clinic
Clinic-listed treatment area Full face

Coverage may be adjusted for the eye area, mouth area, neck or selected local concerns.

Clinic-listed treatment time About 20–30 minutes

Consultation, photography, numbing and preparation may require additional time.

Preparation Topical numbing

The injection method may still produce stinging, pressure or temporary discomfort.

Developing response Around 2–4 weeks

Timing and degree of change vary according to the skin and treatment plan.

What Is Rejuran?

A polynucleotide injectable for selected skin-quality concerns.

Rejuran contains purified polynucleotides derived from salmon DNA. It is injected into selected skin layers with the aim of supporting the local skin environment and gradual improvements in overall skin quality.

The treatment is commonly discussed for fine lines, reduced elasticity, dryness, fragile-looking skin and uneven texture rather than for immediate facial projection or contour.

Skin concerns that look similar can have different causes. Dehydration, active inflammation, sun damage, muscle movement, volume loss and skin laxity may require different treatment approaches.

Rejuran does not permanently erase pores or wrinkles, tighten significant loose skin, replace missing facial volume or reproduce a surgical result.

Skin renewal is different from filling or lifting.

Rejuran is selected with a skin-conditioning objective. Dermal filler creates physical volume, Botox reduces selected muscle activity and lifting devices target selected tissue laxity or firmness.

PN Skin Renewal Concept
Concern 01

Fragile Skin

Thin or stressed-looking skin requires assessment of barrier condition and previous procedures.

Concern 02

Dehydration

Internal dryness may be discussed alongside skincare, environment and inflammatory conditions.

Concern 03

Texture

Uneven texture may involve pores, scars, sensitivity or sun-related change.

Concern 04

Elasticity

Early skin softness differs from significant tissue laxity requiring lifting assessment.

Treatment Framework

Rejuran supports the skin through a gradual treatment response.

Rejuran is injected into multiple selected points across the treatment area. Temporary raised injection marks may appear before the skin settles and the later response can be evaluated.

01

Intradermal Placement

Small amounts are placed across the planned area according to skin thickness, sensitivity and concern.

02

Temporary Embossing

Small raised points may remain visible after treatment and commonly settle as the injected material disperses.

03

Gradual Skin Response

Changes in hydration, texture, fine lines or resilience are assessed over time rather than immediately.

04

Review Before Repeating

Further treatment should follow assessment of response, remaining concerns and any adverse effects.

Concerns Commonly Discussed

The treatment plan begins with your actual skin condition.

These concerns may have several causes. Rejuran is selected only when the proposed injection approach is appropriate for the skin and treatment goal.

01

Fine Lines

Selected fine lines may be assessed according to skin thickness, movement, hydration, sun exposure and surrounding facial support.

Dynamic lines may need another approach
02

Internal Dryness

Persistent dryness may be discussed with barrier health, skincare, climate, medication and underlying skin conditions.

Skincare remains important
03

Reduced Elasticity

Early loss of skin resilience may be assessed, but significant laxity may require energy-based or surgical consultation.

Not a surgical lift
04

Eye-Area Skin

Thin under-eye skin and fine lines may be discussed after assessing hollowness, pigment, vessels, swelling and eyelid support.

Dark circles have several causes
05

Uneven Texture

Roughness or irregular texture may be reviewed alongside acne activity, scarring, sensitivity and previous laser procedures.

Active inflammation requires review
06

Stressed-Looking Skin

Skin affected by repeated procedures, environmental stress or age-related change may require a gentle, staged treatment plan.

Treatment intensity is individual
Injectable Comparison

Rejuran, Juvelook and filler target different concerns.

Product composition, treatment depth, expected response and the type of concern determine which option may be discussed.

01

Rejuran

A polynucleotide injectable selected primarily for gradual skin-conditioning and skin-quality support.

Fine lines and fragile-looking skin Hydration and texture concerns Multiple intradermal injection points Gradual rather than structural volume
Primary focus: skin renewal
02

Juvelook Skin Booster

A PDLLA and hyaluronic-acid treatment discussed for selected texture, pore, fine-line and shallow-scar concerns.

Collagen-support objective Enlarged-looking pores Selected depressed scars Product preparation is important
Primary focus: texture and collagen
03

Dermal Filler

An injectable gel used to create immediate physical volume, structural support or selected facial contour.

Immediate volume change Cheek, chin or lip design Product-specific structural support Separate vascular-safety planning
Primary focus: volume and structure
LOUAVE Treatment Process

Even coverage begins with individual skin assessment.

LOUAVE’s process includes consultation, topical numbing, cleansing, planned injection and calming post-treatment care.

01

Consultation

Skin condition, goals, medical history, medications, allergies and previous procedures are reviewed.

Individual suitability assessment
02

Numbing

Topical numbing cream is applied to reduce discomfort before the injection process begins.

Sensation still varies
03

Cleansing & Mapping

The skin is cleansed and disinfected before treatment coverage and injection points are planned.

Coverage is selected individually
04

Precise Injection

Small amounts are injected evenly across the selected skin area according to thickness and concern.

Temporary raised points may appear
05

Calming Care

The skin is reviewed before calming care, recovery guidance and warning symptoms are explained.

Post-treatment support
Results & Recovery

Injection marks settle before the later response develops.

The immediate appearance may include small raised points, redness, swelling or bruising. These temporary effects are different from the gradual skin-quality response.

Treatment Day

Raised points may be visible

Temporary embossing, redness, tenderness, swelling and pinpoint bruising may occur.

Early Recovery

Injection marks begin settling

LOUAVE notes that raised injection marks commonly settle within approximately one to two days.

Following Weeks

Gradual changes may appear

The clinic lists the developing response from around two to four weeks, although individual timing varies.

Clinical Review

Further treatment is reassessed

The remaining concern, skin response and any adverse effects should be reviewed before repeating treatment.

Skin assessment following Rejuran treatment

International patients should allow time for temporary raised points, redness, swelling or bruising to settle and should avoid scheduling treatment immediately before an important event or departure.

Suitability & Screening

Skin-renewal treatment still requires a medical decision.

Treatment may be delayed, adjusted or declined when active skin disease, health history, previous procedures or expectations make the proposed plan unsuitable.

Rejuran may be discussed when:

  • Fine lines, dryness or fragile-looking skin are primary concerns.
  • Selected texture or early elasticity concerns are being assessed.
  • Thin eye-area, mouth-area or neck skin requires a conservative skin-quality approach.
  • You prefer gradual skin conditioning rather than immediate structural augmentation.
  • You understand that response, duration and treatment frequency vary.

Tell the doctor before treatment about:

  • Pregnancy, planned pregnancy or breastfeeding.
  • Active acne, infection, cold sores, dermatitis, inflammation or an open wound.
  • Fish-related allergies, significant allergies or a previous injectable reaction.
  • Autoimmune disease, bleeding conditions or medicines and supplements that affect bleeding.
  • Previous fillers, skin boosters, collagen stimulators, lasers, threads, surgery or injectable complications.
Aftercare

Protect the skin while the injection sites settle.

Follow the instructions provided by the treating doctor. Advice may vary according to coverage, injection depth, skin sensitivity and medical history.

01

Avoid Unplanned Pressure

Do not aggressively rub, massage, press or manipulate the treated points unless specifically instructed.

02

Manage Heat & Exercise

Ask when strenuous exercise, sauna, intense heat, swimming and alcohol can safely be resumed.

03

Use Gentle Skincare

Follow guidance regarding cleansing, makeup, exfoliation, active ingredients and sun protection.

04

Report Unexpected Symptoms

Contact the clinic for increasing pain, heat, spreading redness, discharge, fever or persistent painful lumps.

Safety Information

Worsening or unusual symptoms should be assessed promptly.

Temporary raised points, redness, swelling, bruising and tenderness may occur. Symptoms that intensify rather than settle require medical review.

Contact the clinic or seek urgent care for:

  • Increasing pain, warmth, spreading redness, discharge or fever.
  • Persistent, enlarging, inflamed or painful lumps.
  • Significant facial swelling, hives or symptoms of an allergic reaction.
  • Pale, grey, mottled or progressively darkening skin.
  • Sudden visual disturbance, severe headache, weakness, difficulty speaking or another neurological symptom.

Breathing difficulty, severe allergic symptoms, visual changes or neurological symptoms require emergency medical attention.

Frequently Asked Questions

Questions about Rejuran treatment.

Product choice, coverage, treatment depth, response and suitability are confirmed during consultation.

What is Rejuran made from?
Rejuran contains purified polynucleotides derived from salmon DNA. Product formulation, indications and availability may vary by country.
Is Rejuran the same as dermal filler?
No. Rejuran is used primarily with a skin-quality and conditioning objective. Dermal filler creates immediate physical volume, projection or structural support.
How is Rejuran different from Juvelook?
Rejuran is a polynucleotide treatment selected for skin-conditioning and renewal concerns. Juvelook combines PDLLA and hyaluronic acid with a collagen-supporting objective for selected texture, pore and scar concerns.
Is Rejuran painful?
Multiple intradermal injections can cause stinging, pressure or discomfort. Topical numbing is used, but sensation varies according to the area and individual sensitivity.
How long do the raised injection marks remain?
LOUAVE notes that temporary raised points commonly settle within approximately one to two days. Larger, painful, inflamed or persistent lumps require assessment.
When may I notice a result?
The clinic lists the developing response from approximately two to four weeks. Timing and degree of change vary according to skin condition and treatment.
How many Rejuran treatments will I need?
There is no single schedule suitable for everyone. Skin condition, response, tolerance, previous procedures and remaining concerns should guide further treatment.
Can Rejuran remove dark circles?
Dark circles may result from pigment, visible vessels, hollowness, thin skin, swelling or shadowing. Rejuran may be discussed for selected thin-skin concerns but cannot correct every cause.
Can Rejuran be combined with Botox or laser treatment?
Combination treatment may be considered when separate muscle, pigment, texture or skin-quality concerns are present. Timing and sequence should be planned individually.
What side effects may occur?
Temporary pain, raised injection points, redness, swelling, tenderness and bruising may occur. Less common concerns include infection, inflammation, allergic reaction, persistent lumps or irregularity.
International Appointment

Plan Rejuran around your skin condition.

Share the concerns you want to discuss, current skin conditions, previous skin boosters, fillers, lasers or lifting treatments, relevant medical information, preferred appointment dates and your Seoul travel schedule. Final product, coverage and treatment plan are confirmed after in-person assessment.

Important treatment information

This page provides general educational information and does not replace an individual medical consultation. Rejuran products contain polynucleotides and have product-specific formulations, indications, contraindications and regulatory status that may vary by country. Treatment must be selected and performed by an appropriately qualified medical professional after reviewing skin condition, facial anatomy, health history, allergies, medications, previous procedures and informed consent. Temporary effects may include injection-site pain, raised points, redness, swelling, tenderness, bruising, itching, firmness or temporary asymmetry. Other complications may include infection, inflammation, allergic reaction, delayed reaction, persistent lumps, pigmentation change, irregularity, scarring or tissue injury. Seek urgent medical assessment for increasing pain, spreading redness, discharge, fever, significant allergic symptoms, progressive skin-colour change, visual disturbance or neurological symptoms. Results, symmetry, response, duration and required treatment frequency vary and cannot be guaranteed.